Women who enter the menopause early has a significant risk of getting Coronary Heart Disease(CHD). According to a new research.
The researchers conducted a review and analysis of 32 previous studies, involving more than 310,000 women.
They said that up to one in 10 women experience natural menopause by the age of 45.
They compared women who experienced menopause younger than 45 and women who were 45 years or older at onset.
The findings, published in the Journal of the American Medical Association, found that overall, women who experienced premature or early-onset menopause appeared to have a greater risk of coronary heart disease and dying as a result of CVD.
But no association was found between the time of the onset of menopause and the risk of suffering a stroke.
Women between the ages of 50 and 54 at the onset of menopause had a decreased risk of fatal coronary heart disease compared with women younger than 50 at onset.
The time since the onset of menopause in relation to the risk of developing intermediate cardiovascular traits or CVD outcomes was reported in four observational studies with inconsistent results.
"However, this review also highlights important gaps in the existing literature and calls for further research to reliably establish whether cardiovascular risk varies in relation to the time since onset of menopause and the mechanisms leading early menopause to cardiovascular outcomes and mortality."
Study author Doctor Taulant Muka, of Erasmus University Medical Centre in Holland, said: "The findings of this review indicate a higher risk of CHD, cardiovascular mortality, and overall mortality in women who experience premature or early-onset menopause when younger than 45.
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